Patent CN1310646C. Medicinal composition containing rotundine for anayesia and giving up drug-takingPDF
Patent CN105949186A Method for preparing L-tetrahydropalmatine sulfate from Stephania kwangsiensisPDF
Patent CN105362272A Pharmaceutical application of rotundinePDF


Effects of rotundine injection on nitric oxide synthaseRESEARCH GATE
Protective effects of tetrahydropalmatine against ketamine-induced learning and memory injury via antioxidative, anti-inflammatory and anti-apoptotic mechanisms in miceSPANDIDOS PUB
Effects of l-tetrahydropalmatine on locomotor sensitization to oxycodone in miceRESEARCH GATE
Study on the stereoselective excretion of tetrahydropalmatine enantiomers in rats and identification of in vivo metabolites by liquid chromatography-tandem mass spectrometry.PUBMED
Correlation between synergistic action of Radix Angelica dahurica extracts on analgesic effects of Corydalis alkaloid and plasma concentration of dl-THP.PUBMED
Tetrahydropalmatine inhibits pro-inflammatory mediators in lipopolysaccharide-stimulated THP-1 cells.PUBMED
Levo-tetrahydropalmatine retards the growth of ectopic endometrial implants and alleviates generalized hyperalgesia in experimentally induced endometriosis in rats.PUBMED
Organic cation transporter 1 mediates the uptake of monocrotaline and plays an important role in its hepatotoxicity.PUBMED
Involvement of organic cation transporter 1 and CYP3A4 in retrorsine-induced toxicity.PUBMED
Development of I-THP as New Medication for Drug Addiction (DP1)University of Maryland Baltimore, Baltimore, MD, United States
Pharmacokinetics and Safety Assessment of l-Tetrahydropalmatine in Cocaine Users: A Randomized, Double-Blind, Placebo-Controlled Study.Hassan, Hazem E; Kelly, Deanna; Honick, Moshe et al. (2017
l-tetrahydropalmatine reduces nicotine self-administration and reinstatement in rats.Faison, Shamia L; Schindler, Charles W; Goldberg, Steven R et al. (2016)
Combination of Levo-Tetrahydropalmatine and Low Dose Naltrexone: A Promising Treatment for Prevention of Cocaine Relapse.Sushchyk, Sarah; Xi, Zheng-Xiong; Wang, Jia Bei (2016)
Simultaneous determination of L-tetrahydropalmatine and cocaine in human plasma by simple UPLC-FLD method: application in clinical studies.Yu, Mingming; Hassan, Hazem E; Ibrahim, Ahmed et al (2014)
l-tetrahydropalamatine: a potential new medication for the treatment of cocaine addictionWang, Jia Bei; Mantsch, John R (2012)
Preparation and Release Test of Rotundinepic Polysaccharide GranulestS. S. Xie,X. J. Liu,Y. X. Zhang,J. L. Zhang,D. Y. Zhang,Y. L. Wang,D. Li &D. Ni
Medication of l-tetrahydropalmatine Significantly Ameliorates Opiate Craving and Increases the Abstinence Rate in Heroin Users: A Pilot StudyZheng Yang, Yong-cong Shao, Shi-Jiang Li,Ming Fan, Mei-Jie Zhang, Wei Hao and Guo-Zhang Jin